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Multifunctional superparamagnetic iron oxide nanoparticles (SPIONs) coated with silica are a promising research field for lots of
biomedical applications. The scope of this work is a preparation of SPIONs and coating them with silica to form core- shell structured
nanoparticles for nanomedicine applications. SPIONs were synthesized by two chemical methods – co-precipitation and thermal
decomposition of organic iron precursor. Prepared nanoparticles were carefully characterized – average size, size distribution,
morphology, crystallinity, colloidal stability and magnetic properties were studied. AŌer comparing SPIONs synthetized by two routes
the most suitable method for biomedical applicable nanoparti cles preparation is determined. The nanomedicine requires
nanoparticles of the highest quality.
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