International Journal of Dental Sciences & Research - Volumes & Issues - Volume 1: July 2021, Issue 1

Assessment of salivary cortisol level in xerostomia patients

  • Published: July 2021
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Authors

Dr Sipra Salaria, Dr. Gagandeep Singh & Dr. Hirdepal Singh Brar

DOI Number

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Keywords

Cortisol, dry mouth, xerostomia

Abstract

Objective: The present study was conducted to assess salivary cortisol level in patients with xerostomia.

Materials & Methods: 52 patients with subjective symptoms of dry mouth (Group I) of both genders. Equal number of healthy subjects was selected as control (Group II) were enrolled. The concentration of cortisol in the saliva (μg/dl) was determined by using a salivary cortisol enzyme immunoassay kit.

Results: Group I had 12 males and 14 females and group II had 16 males and 10 females. The mean cortisol level in group I was 2.38 μg/dl and in group II was 1.90μg/dl. The difference was significant (P<0.05).

Conclusion: There was low level of salivary cortisol in xerostomia patients.

References

  1. Bergdahl M, Bergdahl J, Johansson I. Depressive symptoms in individuals with idiopathic subjective dry mouth. J Oral Pathol Med. 1997; 26: 448-50.
  2. Miyakawa M, Matsui T, Kishikawa H, Murayama R, Uchiyama I, Itoh T, et al. Salivary chromogranin A as a measure of stress response to noise. Noise Health. 2006; 8:108-13.
  3. Vining RF, McGinley RA, Symons RG. Hormones in saliva: Mode of entry and consequent implications for clinical interpretation. Clin Chem. 1983; 29:1752-6.
  4. Obmi ski Z, Wojtkowiak M, Stupnicki R, Golec L, Hackney AC. Effect of acceleration stress on salivary cortisol and plasma cortisol and testosterone levels in cadet pilots. J PhysiolPharmacol. 1997; 48:193-200.
  5. Hill CM, Walker RV. Salivary cortisol determinations and self rating scales in the assessment of stress in patients undergoing the extraction of wisdom teeth. Br Dent J. 2001;191:513-5.
  6. Bains SK, Bhatia A. A single drop can diagnose many- Salivary diagnosis. J Stomatognathic Scie. 2014;4(1):15 20.
  7. Levine A, Zagoory-Sharon O, Feldman R, Lewis JG, Weller A. Measuring cortisol in human psychobiological studies. PhysiolBehav. 2007;90:43-53.
  8. Sreebny LM, Validini A, Yu A. Xerostomia. Part II: Relationship to non oral symptoms, drugs, and diseases. Oral Surg Oral Med Oral Pathol. 1989; 68:419-27.
  9. Orellana MF, Lagravère MO, Boychuk DG, Major PW, Flores- Mir C. Prevalence of xerostomia in population-based samples: A systematic review. J Public Health Dent. 2006; 66:152-8.
  10. Shekar V, Austin RD, Mathew P. A case control study to evaluate salivary cortisol levels in patients with dry mouth. J Indian Acad Oral Med Radiol2014;26:8-12.
  11. Rivera Gómez MB, Hernández Vallejo G, Arriba de la Fuente L, López Cantor M, Díaz Rodríguez M, López Pintor Muñoz RM. The relationship between the levels of salivary cortisol and the presence of xerostomia in menopausal women: a preliminary study.Med Oral Patol Oral Cir Bucal 2006;11:407-12.
  12. Vaseemuddin S. Evaluation of salivary cortisol level and salivary flow in xerostomia: A clinical study. Int J Res Health Allied Sci 2016;2(4):47-50.
  13. 13. Pajukoski H, Meurman JH, Halonen P, Sulkava R. Prevalence of subjective dry mouth and burning mouth in hospitalized elderly patients and outpatients in relation to saliva, medication, and systemic diseases. Oral Surg Oral Med Oral Pathol Oral RadiolEndod2001;92:641-9

How to cite

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Journal

International Journal of Dental Sciences & Research

ISSN

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Periodicity

Bi-Annual

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