Background: Microorganisms play an essential role in pulpal and periapical diseases. The present study compared antimicrobial efficacy of calcium silicate based material bio dentine, MTA and Theracal LC.
Materials & Methods: The present study comprised of three materials such as MTA (Group I), Bio dentine (Group II) and Theracal LC (Group III). The antibacterial efficacy of these materials was evaluated and minimal bacterial count (CFU’s) against Enterococcus fecalis and candida albicanswas tested using tube dilution method.
Results: The mean CFU of candida in group I was 69.2, in group II was 70.4 and in group III was 76.3. The difference was significant (P< 0.05). The mean CFU of E. fecalis in group I was 46.5, in group II was 59.2 and in group III was 54.1. The difference was significant (P< 0.05). Conclusion: Antibacterial activity of Biodentine was superior than an-bacterial as compared to MTA angelus and theracal LC.